| Heimtabelle | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Pl. | Pl. | Verein | Sp. | Ge | Un | Ve | Tore | Diff | Pkte |
| 1. | (1) | TuS Bövinghausen | 16 | 12 | 2 | 2 | 45:14 | 31 | 38 |
| 2. | (2) | DSC Wanne-Eickel | 17 | 10 | 2 | 5 | 42:24 | 18 | 32 |
| 3. | (3) | YEG Hassel 1993 | 16 | 10 | 2 | 4 | 36:29 | 7 | 32 |
| 4. | (4) | FC Iserlohn 46/49 | 16 | 9 | 3 | 4 | 37:23 | 14 | 30 |
| 5. | (5) | SV Sodingen | 16 | 9 | 3 | 4 | 31:20 | 11 | 30 |
| 6. | (6) | DJK TuS Hordel | 15 | 9 | 2 | 4 | 38:23 | 15 | 29 |
| 7. | (7) | SV Wacker Obercastrop | 16 | 9 | 2 | 5 | 28:19 | 9 | 29 |
| 8. | (8) | FC Brünninghausen | 16 | 8 | 3 | 5 | 34:19 | 15 | 27 |
| 9. | (11) | SV Concordia Wiemelhausen | 16 | 7 | 5 | 4 | 35:23 | 12 | 26 |
| 10. | (9) | FC Lennestadt | 16 | 7 | 5 | 4 | 26:23 | 3 | 26 |
| 11. | (10) | SV Rot-Weiß Deuten | 16 | 7 | 3 | 6 | 32:26 | 6 | 24 |
| 12. | (16) | FSV Gerlingen | 16 | 6 | 3 | 7 | 28:32 | -4 | 21 |
| 13. | (12) | BSV Schüren | 16 | 5 | 5 | 6 | 34:29 | 5 | 20 |
| 14. | (13) | Westfalia Wickede | 16 | 5 | 5 | 6 | 29:26 | 3 | 20 |
| 15. | (14) | SC Neheim | 16 | 6 | 2 | 8 | 26:28 | -2 | 20 |
| 16. | (15) | SV Hohenlimburg | 16 | 6 | 2 | 8 | 24:39 | -15 | 20 |
| 17. | (18) | SpVgg Hagen | 16 | 4 | 2 | 10 | 31:43 | -12 | 14 |
| 18. | (17) | Borussia Dröschede | 16 | 2 | 6 | 8 | 21:31 | -10 | 12 |
Relegation: 09.06.2022 1. FC Gievenbeck - DJK TuS Hordel 3:1 (1:0)
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