| Rückrundentabelle | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Pl. | Pl. | Verein | Sp. | Ge | Un | Ve | Tore | Diff | Pkte |
| 1. | (1) | TuS Bövinghausen | 16 | 14 | 1 | 1 | 55:14 | 41 | 43 |
| 2. | (2) | DJK TuS Hordel | 16 | 10 | 2 | 4 | 40:26 | 14 | 32 |
| 3. | (3) | YEG Hassel 1993 | 16 | 9 | 5 | 2 | 39:28 | 11 | 32 |
| 4. | (4) | FC Brünninghausen | 16 | 8 | 3 | 5 | 30:23 | 7 | 27 |
| 5. | (9) | FC Lennestadt | 16 | 7 | 3 | 6 | 28:29 | -1 | 24 |
| 6. | (10) | SV Rot-Weiß Deuten | 16 | 7 | 3 | 6 | 37:39 | -2 | 24 |
| 7. | (5) | BSV Schüren | 16 | 6 | 5 | 5 | 33:28 | 5 | 23 |
| 8. | (6) | FC Iserlohn 46/49 | 16 | 6 | 4 | 6 | 27:23 | 4 | 22 |
| 9. | (7) | DSC Wanne-Eickel | 16 | 6 | 3 | 7 | 31:25 | 6 | 21 |
| 10. | (8) | SV Concordia Wiemelhausen | 16 | 6 | 3 | 7 | 32:31 | 1 | 21 |
| 11. | (11) | SV Wacker Obercastrop | 16 | 6 | 2 | 8 | 26:26 | 0 | 20 |
| 12. | (12) | SpVgg Hagen | 16 | 6 | 2 | 8 | 32:40 | -8 | 20 |
| 13. | (13) | FSV Gerlingen | 16 | 6 | 2 | 8 | 30:40 | -10 | 20 |
| 14. | (15) | SC Neheim | 16 | 6 | 1 | 9 | 26:28 | -2 | 19 |
| 15. | (14) | SV Sodingen | 16 | 6 | 0 | 10 | 30:52 | -22 | 18 |
| 16. | (17) | SV Hohenlimburg | 16 | 5 | 2 | 9 | 24:44 | -20 | 17 |
| 17. | (16) | Westfalia Wickede | 16 | 4 | 3 | 9 | 23:31 | -8 | 15 |
| 18. | (18) | Borussia Dröschede | 16 | 1 | 6 | 9 | 9:25 | -16 | 9 |
Relegation: 09.06.2022 1. FC Gievenbeck - DJK TuS Hordel 3:1 (1:0)
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